Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 2.013


Transcription factors associated with FOS_FOS{B,L1}_JUN{B,D}.p2:

Gene SymbolEntrez IDGene Name
FOS 2353 v-fos FBJ murine osteosarcoma viral oncogene homolog
FOSB 2354 FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 8061 FOS-like antigen 1
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOSL1chr11_-_656678600.502.8e-15Click!
JUNDchr19_-_18392048-0.252.0e-04Click!
JUNBchr19_+_12902295-0.211.9e-03Click!
FOSchr14_+_75745480-0.152.5e-02Click!
FOSBchr19_+_45971249-0.127.3e-02Click!


Activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2.

activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2


Sorted Z-values histogram for motif FOS_FOS{B,L1}_JUN{B,D}.p2

Sorted Z-values for motif FOS_FOS{B,L1}_JUN{B,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOS_FOS{B,L1}_JUN{B,D}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_223889253 64.017 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr18_+_21452981 43.779 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr3_-_149095413 39.956 TM4SF1
transmembrane 4 L six family member 1
chr1_+_156084565 39.685 LMNA
lamin A/C
chr1_+_156084541 39.127 LMNA
lamin A/C
chr12_+_13349601 37.633 NM_001423
EMP1
epithelial membrane protein 1
chr3_-_149095517 36.573 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr3_-_149095458 35.896 TM4SF1
transmembrane 4 L six family member 1
chr1_+_156084458 34.716 NM_005572
NM_170707
NM_170708
LMNA


lamin A/C


chr3_-_149095333 33.347 TM4SF1
transmembrane 4 L six family member 1
chr6_+_83072922 31.453 NM_006670
TPBG
trophoblast glycoprotein
chr12_+_13349720 31.238 EMP1
epithelial membrane protein 1
chr12_-_53343607 29.870 KRT8
keratin 8
chr1_-_95007139 26.822 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr7_+_73245192 25.525 NM_001305
CLDN4
claudin 4
chr2_-_216259197 25.482 FN1
fibronectin 1
chr6_-_138428477 23.100 NM_022121
PERP
PERP, TP53 apoptosis effector
chr5_+_150020201 22.813 NM_001109974
NM_007286
SYNPO

synaptopodin

chr1_+_183155393 21.650 LAMC2
laminin, gamma 2
chr16_-_69760444 21.272 NM_000903
NM_001025433
NM_001025434
NQO1


NAD(P)H dehydrogenase, quinone 1


chr7_-_16844606 20.824 NM_006408
AGR2
anterior gradient 2 homolog (Xenopus laevis)
chr1_-_152009440 20.510 S100A11
S100 calcium binding protein A11
chr1_-_152009406 20.163 S100A11
S100 calcium binding protein A11
chr1_+_223900226 19.976 CAPN2
calpain 2, (m/II) large subunit
chr11_-_2950593 19.883 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr1_-_209824641 19.455 NM_001017402
LAMB3
laminin, beta 3
chr11_-_65667858 18.801 FOSL1
FOS-like antigen 1
chr11_+_394199 18.713 NM_007183
PKP3
plakophilin 3
chr1_+_223900212 18.493 CAPN2
calpain 2, (m/II) large subunit
chr15_-_60690115 18.438 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr7_-_107643330 18.414 NM_002291
LAMB1
laminin, beta 1
chr10_+_121410751 18.393 NM_004281
BAG3
BCL2-associated athanogene 3
chr11_-_33744497 18.184 NM_001127227
CD59
CD59 molecule, complement regulatory protein
chr11_-_65667809 17.834 FOSL1
FOS-like antigen 1
chr1_+_27189628 17.622 NM_006142
SFN
stratifin
chr13_-_38172862 17.610 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr1_+_156084579 17.554 LMNA
lamin A/C
chr5_+_140868721 17.436 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr11_-_65667860 17.221 NM_005438
FOSL1
FOS-like antigen 1
chr11_+_394238 16.938 PKP3
plakophilin 3
chr10_+_121410891 16.664 BAG3
BCL2-associated athanogene 3
chr15_+_22892723 16.196 CYFIP1
cytoplasmic FMR1 interacting protein 1
chr17_+_30771520 16.006 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr21_-_27543134 15.882 NM_000484
NM_001136129
NM_001136130
NM_001204301
NM_001204302
NM_001204303
NM_201413
NM_201414
APP







amyloid beta (A4) precursor protein







chr1_-_153538305 15.529 NM_005978
S100A2
S100 calcium binding protein A2
chr15_+_22892714 15.522 CYFIP1
cytoplasmic FMR1 interacting protein 1
chr1_-_152009467 14.789 S100A11
S100 calcium binding protein A11
chr21_-_27543445 14.639 NM_001136131
APP
amyloid beta (A4) precursor protein
chr21_-_27512668 14.629 NM_001136016
APP
amyloid beta (A4) precursor protein
chr5_+_138089118 14.462 CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr7_+_116312412 14.361 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr20_-_43977023 14.354 NM_002999
SDC4
syndecan 4
chr6_+_121756744 14.275 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr5_+_138089073 14.033 NM_001903
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr4_+_169753105 13.861 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr16_+_56642477 13.702 NM_005953
MT2A
metallothionein 2A
chr13_+_97794050 13.632 MBNL2
muscleblind-like 2 (Drosophila)
chr21_-_27543044 13.551 APP
amyloid beta (A4) precursor protein
chr1_-_152009490 13.528 NM_005620
S100A11
S100 calcium binding protein A11
chr10_+_121411042 13.028 BAG3
BCL2-associated athanogene 3
chr10_+_121411071 12.968 BAG3
BCL2-associated athanogene 3
chr3_+_183894736 12.941 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr12_-_91573264 12.928 NM_133503
DCN
decorin
chr11_-_8739398 12.787 ST5
suppression of tumorigenicity 5
chr6_-_84140758 12.766 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr15_-_56209305 12.702 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr11_-_6341708 12.498 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr12_-_52886971 12.359 NM_005554
KRT6A
keratin 6A
chr3_+_100238063 12.334 TMEM45A
transmembrane protein 45A
chr11_-_33744272 12.313 NM_001127223
NM_001127225
NM_001127226
CD59


CD59 molecule, complement regulatory protein


chr11_+_101983170 12.263 NM_001195045
YAP1
Yes-associated protein 1
chr1_+_153003677 12.229 NM_003125
SPRR1B
small proline-rich protein 1B
chr13_+_78109808 12.155 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr7_+_48128225 11.818 NM_181597
UPP1
uridine phosphorylase 1
chr12_-_56122840 11.405 NM_001040034
NM_001780
CD63

CD63 molecule

chr9_+_71819926 11.397 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr12_-_56122792 11.337 CD63
CD63 molecule
chr2_+_47596447 11.206 EPCAM
epithelial cell adhesion molecule
chr1_+_183155361 10.996 LAMC2
laminin, gamma 2
chr12_-_56122800 10.952 CD63
CD63 molecule
chrX_+_47441650 10.937 NM_003254
TIMP1
TIMP metallopeptidase inhibitor 1
chr3_-_123339178 10.925 MYLK
myosin light chain kinase
chr8_-_27472188 10.576 CLU
clusterin
chr4_+_74606222 10.393 NM_000584
IL8
interleukin 8
chr1_-_154943001 10.372 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr15_+_22892683 10.303 NM_014608
CYFIP1
cytoplasmic FMR1 interacting protein 1
chr18_+_61144143 10.251 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr6_+_30856462 10.220 NM_001202521
NM_001202522
NM_013994
DDR1


discoidin domain receptor tyrosine kinase 1


chr12_-_56122748 10.164 CD63
CD63 molecule
chr17_-_39743085 10.148 NM_000526
KRT14
keratin 14
chr17_-_39768939 10.116 NM_005557
KRT16
keratin 16
chr1_-_27816542 10.104 WASF2
WAS protein family, member 2
chr15_+_22892517 9.872 CYFIP1
cytoplasmic FMR1 interacting protein 1
chr5_+_140729723 9.862 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr19_-_39264144 9.768 NM_002307
LGALS7
LGALS7B
lectin, galactoside-binding, soluble, 7
lectin, galactoside-binding, soluble, 7B
chr6_-_84140744 9.741 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chrX_-_15511358 9.731 PIR
pirin (iron-binding nuclear protein)
chr20_+_33759773 9.711 NM_006404
PROCR
protein C receptor, endothelial
chr1_+_81771844 9.643 LPHN2
latrophilin 2
chr19_-_44174497 9.575 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chrX_+_135251795 9.559 NM_001167819
FHL1
four and a half LIM domains 1
chr1_+_150480486 9.506 NM_001202858
NM_004425
NM_022664
ECM1


extracellular matrix protein 1


chr16_+_89988416 9.452 NM_001197181
TUBB3
tubulin, beta 3 class III
chr8_-_12973752 9.404 NM_001164271
DLC1
deleted in liver cancer 1
chr20_+_19867075 9.401 NM_001242581
RIN2
Ras and Rab interactor 2
chr1_+_150480584 9.310 ECM1
extracellular matrix protein 1
chr11_+_67351276 9.237 GSTP1
glutathione S-transferase pi 1
chr11_+_706103 9.190 NM_022772
EPS8L2
EPS8-like 2
chr1_+_223900061 9.067 NM_001748
CAPN2
calpain 2, (m/II) large subunit
chr11_-_102668822 8.956 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chrX_+_99899388 8.879 SRPX2
sushi-repeat containing protein, X-linked 2
chr11_-_102668892 8.869 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr17_-_48278874 8.865 COL1A1
collagen, type I, alpha 1
chr10_+_17270469 8.865 VIM
vimentin
chr11_-_102401430 8.810 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr1_-_86043932 8.771 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr17_-_39942937 8.698 NM_002230
NM_021991
JUP

junction plakoglobin

chr17_+_80193649 8.648 NM_001206952
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr6_-_84140854 8.637 NM_002395
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr10_-_5060191 8.558 NM_001354
NM_205845
AKR1C2

aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)

chr15_+_41136178 8.544 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr1_+_183155173 8.536 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chrX_+_99899162 8.443 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr7_-_93519990 8.332 NM_006528
TFPI2
tissue factor pathway inhibitor 2
chr5_-_149535420 8.301 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr3_-_123339423 8.290 NM_053031
NM_053032
MYLK

myosin light chain kinase

chrX_-_15511710 8.247 NM_001018109
NM_003662
PIR

pirin (iron-binding nuclear protein)

chr21_-_27542919 8.224 APP
amyloid beta (A4) precursor protein
chr1_+_32043745 8.200 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr19_-_291335 8.156 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr2_+_170366211 8.140 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr22_+_38598065 8.072 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr9_+_140172273 8.040 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr10_+_123872440 7.991 TACC2
transforming, acidic coiled-coil containing protein 2
chr15_+_22892699 7.977 CYFIP1
cytoplasmic FMR1 interacting protein 1
chr2_+_28615695 7.968 FOSL2
FOS-like antigen 2
chr1_-_156675237 7.854 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chr17_-_39675078 7.787 NM_002275
KRT15
keratin 15
chr15_+_41136622 7.765 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr21_-_27543060 7.706 APP
amyloid beta (A4) precursor protein
chr22_-_30642683 7.705 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chrX_-_10851808 7.700 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr14_+_103800678 7.529 EIF5
eukaryotic translation initiation factor 5
chr10_-_93392857 7.505 NM_005398
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr20_-_6104056 7.482 NM_017671
FERMT1
fermitin family member 1
chr1_-_24126031 7.479 NM_001127621
GALE
UDP-galactose-4-epimerase
chr7_+_22766765 7.475 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chr10_-_98346594 7.442 TM9SF3
transmembrane 9 superfamily member 3
chr14_-_75643309 7.440 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr7_+_23286390 7.305 GPNMB
glycoprotein (transmembrane) nmb
chr20_+_34742656 7.262 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr17_+_28268622 7.243 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr12_-_106533810 7.128 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr10_+_5136589 7.115 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_17270257 7.093 NM_003380
VIM
vimentin
chr11_-_118135197 7.090 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr12_+_56546203 7.080 NM_001199629
NM_002475
MYL6B

myosin, light chain 6B, alkali, smooth muscle and non-muscle

chr7_+_23286277 7.039 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr3_+_105085553 7.009 NM_001243280
NM_001243281
NM_001243283
NM_001627
ALCAM



activated leukocyte cell adhesion molecule



chr17_+_18625335 6.960 NM_001037330
TRIM16L
tripartite motif containing 16-like
chr18_+_61442611 6.943 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr17_-_65362667 6.922 NM_002816
NM_174871
PSMD12

proteasome (prosome, macropain) 26S subunit, non-ATPase, 12

chr11_-_118134986 6.780 MPZL2
myelin protein zero-like 2
chr14_-_75643333 6.761 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr19_-_291168 6.705 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr17_+_74380943 6.690 SPHK1
sphingosine kinase 1
chr17_+_30771522 6.667 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_-_244006471 6.655 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr11_+_46402333 6.627 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr7_+_134212343 6.572 NM_020299
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr6_-_10419786 6.549 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr20_+_4666796 6.548 NM_000311
NM_001080121
NM_001080122
NM_183079
NM_001080123
PRNP




prion protein




chr16_+_57662301 6.534 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr10_+_121411086 6.456 BAG3
BCL2-associated athanogene 3
chr2_-_65593866 6.433 NM_001128210
SPRED2
sprouty-related, EVH1 domain containing 2
chr11_-_62314291 6.427 NM_001620
NM_024060
AHNAK

AHNAK nucleoprotein

chr2_+_62934030 6.365 NM_001142614
EHBP1
EH domain binding protein 1
chr7_+_23286384 6.312 GPNMB
glycoprotein (transmembrane) nmb
chr3_-_151034514 6.299 NM_023915
GPR87
G protein-coupled receptor 87
chr17_+_30771532 6.288 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_-_153935190 6.268 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr21_-_36421578 6.224 RUNX1
runt-related transcription factor 1
chr19_+_39279849 6.169 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr17_+_30771494 6.155 NM_002815
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_-_39780762 6.145 NM_000422
KRT17
keratin 17
chr17_+_30771485 6.123 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr19_-_51472816 6.121 NM_002774
KLK6
kallikrein-related peptidase 6
chr7_+_112063131 6.110 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr10_-_93392744 6.104 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr2_-_166650770 6.092 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr22_+_38597938 6.068 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr3_-_98241357 6.031 CLDND1
claudin domain containing 1
chr18_+_55888838 6.006 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr7_+_23286420 5.998 GPNMB
glycoprotein (transmembrane) nmb
chr10_+_5136613 5.983 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr5_+_73981055 5.944 HEXB
hexosaminidase B (beta polypeptide)
chr18_+_55888799 5.906 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr5_+_73980968 5.895 NM_000521
HEXB
hexosaminidase B (beta polypeptide)
chr8_-_103666018 5.882 NM_001032282
KLF10
Kruppel-like factor 10
chr19_-_44174271 5.874 PLAUR
plasminogen activator, urokinase receptor

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.63 6.04e-14 GO:0048856 anatomical structure development
1.66 2.31e-13 GO:0048731 system development
1.53 1.95e-12 GO:0032502 developmental process
1.56 5.28e-12 GO:0007275 multicellular organismal development
2.16 2.08e-09 GO:0009888 tissue development
1.37 3.52e-09 GO:0032501 multicellular organismal process
1.68 5.05e-08 GO:0048513 organ development
1.15 5.42e-07 GO:0009987 cellular process
1.61 5.45e-07 GO:0030154 cell differentiation
1.92 2.03e-06 GO:0042127 regulation of cell proliferation
1.58 2.47e-06 GO:0048869 cellular developmental process
1.93 4.14e-06 GO:0009611 response to wounding
1.93 9.04e-06 GO:0040011 locomotion
1.68 1.08e-05 GO:0009653 anatomical structure morphogenesis
1.50 1.26e-05 GO:0048522 positive regulation of cellular process
1.47 1.29e-05 GO:0048518 positive regulation of biological process
2.14 1.30e-05 GO:0042060 wound healing
1.22 1.52e-05 GO:0065007 biological regulation
1.99 1.56e-05 GO:0007155 cell adhesion
1.99 1.56e-05 GO:0022610 biological adhesion
1.88 2.03e-05 GO:0048468 cell development
3.07 2.04e-05 GO:0008544 epidermis development
1.22 6.50e-05 GO:0050789 regulation of biological process
2.09 1.07e-04 GO:0050878 regulation of body fluid levels
1.22 1.27e-04 GO:0050794 regulation of cellular process
1.48 1.50e-04 GO:0042221 response to chemical stimulus
2.59 1.78e-04 GO:0061061 muscle structure development
1.59 7.36e-04 GO:0007399 nervous system development
1.46 9.77e-04 GO:0048523 negative regulation of cellular process
1.46 1.11e-03 GO:0065008 regulation of biological quality
1.43 1.18e-03 GO:0006950 response to stress
1.23 1.18e-03 GO:0050896 response to stimulus
1.44 1.19e-03 GO:0048519 negative regulation of biological process
1.62 1.32e-03 GO:0051239 regulation of multicellular organismal process
1.30 1.79e-03 GO:0051716 cellular response to stimulus
2.02 1.83e-03 GO:0008284 positive regulation of cell proliferation
1.32 1.85e-03 GO:0023052 signaling
1.74 1.89e-03 GO:0050793 regulation of developmental process
4.66 2.46e-03 GO:0006521 regulation of cellular amino acid metabolic process
1.97 2.57e-03 GO:0006928 cellular component movement
1.33 4.32e-03 GO:0007165 signal transduction
1.80 4.34e-03 GO:2000026 regulation of multicellular organismal development
2.69 4.40e-03 GO:0007517 muscle organ development
2.01 4.60e-03 GO:0007596 blood coagulation
2.01 4.60e-03 GO:0050817 coagulation
1.64 4.65e-03 GO:0051246 regulation of protein metabolic process
1.99 5.59e-03 GO:0007599 hemostasis
1.65 5.94e-03 GO:0010646 regulation of cell communication
2.03 6.80e-03 GO:0048870 cell motility
2.03 6.80e-03 GO:0051674 localization of cell
1.70 6.84e-03 GO:0022008 neurogenesis
1.74 2.73e-02 GO:0006915 apoptosis
3.86 2.73e-02 GO:0033238 regulation of cellular amine metabolic process
2.87 2.93e-02 GO:0032496 response to lipopolysaccharide
9.63 2.94e-02 GO:0031581 hemidesmosome assembly
1.84 3.13e-02 GO:0048666 neuron development
2.00 3.21e-02 GO:0016477 cell migration
1.53 3.32e-02 GO:0010033 response to organic substance
3.53 4.23e-02 GO:0048871 multicellular organismal homeostasis
1.72 4.41e-02 GO:0012501 programmed cell death
1.97 4.72e-02 GO:0043086 negative regulation of catalytic activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 2.08e-05 GO:0005737 cytoplasm
2.88 2.26e-05 GO:0005911 cell-cell junction
1.81 5.61e-05 GO:0005626 insoluble fraction
1.46 6.23e-05 GO:0044459 plasma membrane part
4.48 1.09e-04 GO:0000502 proteasome complex
1.78 2.40e-04 GO:0005624 membrane fraction
7.56 3.35e-04 GO:0001533 cornified envelope
1.63 4.51e-04 GO:0000267 cell fraction
1.87 8.76e-04 GO:0030054 cell junction
1.50 1.39e-03 GO:0005856 cytoskeleton
3.12 1.87e-03 GO:0044420 extracellular matrix part
2.87 6.91e-03 GO:0043292 contractile fiber
2.57 7.42e-03 GO:0070161 anchoring junction
2.38 9.20e-03 GO:0030141 stored secretory granule
2.89 9.97e-03 GO:0030016 myofibril
1.24 1.32e-02 GO:0071944 cell periphery
1.55 1.36e-02 GO:0044421 extracellular region part
2.24 1.57e-02 GO:0016323 basolateral plasma membrane
9.80 2.16e-02 GO:0005838 proteasome regulatory particle
2.81 2.35e-02 GO:0044449 contractile fiber part
1.23 2.94e-02 GO:0005886 plasma membrane
1.91 3.21e-02 GO:0031012 extracellular matrix
1.35 3.33e-02 GO:0005576 extracellular region
2.98 4.87e-02 GO:0016327 apicolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.27 3.72e-09 GO:0005515 protein binding
1.11 5.06e-04 GO:0005488 binding
1.59 7.44e-03 GO:0005102 receptor binding
1.78 2.36e-02 GO:0008092 cytoskeletal protein binding
2.56 2.80e-02 GO:0061135 endopeptidase regulator activity
2.54 4.51e-02 GO:0004866 endopeptidase inhibitor activity